KKALRRQEAVDAL，高度特异性的、CaMKII的有效抑制剂

Autocamtide-2-related inhibitory peptide (TFA) 是高度特异性的、CaMKII 的有效抑制剂，其 IC50 值为 40 nM。

It is found that Autocamtide-2-related inhibitory peptide (TFA) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93, respectively, under the assay condition used

单字母 H2N-KKALRRQEAVDAL-OH

多字母 H2N-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH

氨基酸个数 13

分子式 C64H116N22O19

平均分子量(MW) 1497.74

精确分子量(Exact Mass)(MW) 1496.88

等电点(PI) 11.66

pH=7.0时的净电荷数 2.98

GRAVY -0.78

亲水残基比例 0.07

消光系数 -

溶解建议 亲水

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